MRNA Scientist
Thermo Fisher Scientific
Monza
30
Discreto
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Azienda: Thermo Fisher Scientific Monza
Esperienza: 5+ anni nel settore, 3+ anni di esperienza significativa in industria o PhD in Biochimica/Chimica/Ingegneria Chimica/Biologia Molecolare
Titolo di studio: PhD in Biochimica/Chimica/Ingegneria Chimica/Biologia Molecolare o aree scientifiche correlate
: Hands-on experience in DNA/RNA extraction, gene expression assays, qRT-PCR, primer design, and gene expression analysis is critical.
The candidate should be able to develop product specifications, feasibility and development experiments, protocols, and procedures, as well as write clear and professional reports to support timely project completion.
The candidate should be proficient in bioinformatics to develop targeted assays and analyze next-generation sequencing (NGS) data.
Experience in developing robust and scalable downstream processes to purify nucleic acids with liquid chromatography (FPLC) is highly desirable. should also design, implement, and fix experiments to optimize assay performance, and provide clear and concise project status updates to internal and external stakeholders.
The candidate should support scale-up of upstream/downstream processes and technology transfer to the cGMP manufacturing and quality control (QC) groups for clinical material production/analysis. should be able to perform routine bench work under limited supervision, prioritize responsibilities effectively, and complete assignments on time.
The candidate should be able to discuss the progress of activities and propose technical solutions with internal and external stakeholders. should also be able to analyze, interpret, and present results to project teams, and write technical reports.
Maintaining domain expertise in new technologies and scientific literature is critical to constantly drive innovation.
The candidate should be able to train junior scientists, as needed Qualifications: with 5+ years of proven experience in the industry, with 3+ years of meaningful experience in industry, or PhD in Biochemistry/ Chemistry/ Chemical Engineering/ Molecular Biology or related scientific subject areas with 0-2 years of proven experience.
Requirements: Expert level understanding and hands on experience with next generation sequencing (NGS) assays and workflows.
Expert level understanding of standard molecular biology techniques including PCR, qPCR, cloning, nucleic acid extraction and quantification, and in-vitro transcription.
Experience with NGS assay development.
Experienced with DNA and RNA sample processing and sample stabilization procedures.
Experience in process development for therapeutics with standard downstream purification techniques, including depth filtration, FPLC and Tangential flow filtration (TFF) is highly desirable.
Familiarity with the process development of mRNA products would be a plus.
Experience with GLP and GMP compliance and manufacturing preferred.
Experience writing content for documentation, including SO Ps, work instructions, technical protocols and reports, and technical presentations.
A high level of commitment and a track record of quality work, with attention to detail.
Capable of presenting the work clearly among the team.
Ability to multi-task and prioritize to meet important deadlines.
Ability to respond quickly to constantly evolving priorities.
A self-starter and great teammate.
Excellent written and spoken English.
Thermo Fisher Scientific is an Equal Opportunity Employer.
All qualified applicants will receive consideration for employment without regard to race, creed, religion, color, national or ethnic origin, citizenship, sex, sexual orientation, gender identity and expression, genetic information, veteran status, age or disability status.
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✔ Thermo Fisher Scientific